With 7:07 left in the first half of Auburn's first SEC road game, the Tigers were tied at 18 with Missouri.
Not much went right for the visitors after that point, as turnovers, foul trouble and poor shooting led to a 76-61 Auburn loss in Columbia.
Tyler Harris led Auburn with 21 points on six of 12 shooting, but his teammates combined to shoot only 33 percent from the floor. Bryce Brown added 11 points and was the only other Auburn player in double figures.
Kareem Canty, who entered the game averaging 19.5 points per game, spent most of the contest in foul trouble and scored only 9 points.
Missouri went on a 21-6 run over the final 7:07 of the first half to take control of the game. The home team grew its lead to as large as 26 in the second half.
Kevin Puryear lead four Missouri players in double figures with 14 points.
Auburn was dominated in bench points for the second consecutive game, as Missouri outscored the Tigers 40-5 after South Carolina's bench outscored Auburn's 24-3 on Tuesday.
Auburn also struggled with turnovers for the second straight game, recording 14 against Missouri after setting a season-high with 21 against the Gamecocks.
Bruce Pearl will take his team on the road again next Tuesday, when Auburn travels to Nashville to face Vanderbilt.
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